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Nattokinase

Supplement1 review
+3
Average score out of 5
Based on 1 experience(s)

Enzyme derived from natto (fermented soy) with fibrinolytic properties, used in Long COVID to help dissolve microclots and improve circulation.

Information
Subcategory
fibrinolytic enzyme
Evidence type
preliminary and preclinical studies
Score distribution
+5
0 (0%)
+3
1 (100%)
+1
0 (0%)
0
0 (0%)
Negative
0 (0%)
Most improved symptoms
Practical information
Time to effect
3+ months
Common dosage
2000 IU
Reported side effects
Made me feel worse at first (1-2 months?) which I heard can happen due to freeing the content of the blood clots in the blood (100%)
Latest reviews
M
Anonymous review+3
26-35 y.o. · 4/26/2026

I wasn't sure if it played in my improvement at first, but when I stopped it after 9 months, my brain fog skyrocketed. Then it went back to normal when I started taking it again. My cognitive state with and without is day and night.

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