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Mirtazapine

MedicationOff-label3 reviews
+2.3
Average score out of 5
Based on 3 experience(s)

A sedating tetracyclic antidepressant used off-label for its sleep-promoting, anxiolytic and appetite-stimulating effects in Long COVID patients.

Brand names
Norset
Information
Subcategory
tetracyclic antidepressant (NaSSA)
Evidence level
3/5
Evidence type
case series and expert consensus
Score distribution
+5
0 (0%)
+3
2 (67%)
+1
1 (33%)
0
0 (0%)
Negative
0 (0%)
Most improved symptoms
Practical information
Time to effect
< 1 week
Reported side effects
Vivid dreams (33%)dry mouth (33%)
Latest reviews
F
Anonymous review+1
18-25 y.o. · 6/30/2026
F
Anonymous review+3
18-25 y.o. · 6/6/2026

The only thing that has helped with my insomnia. I take a small dose of around 1.5mgs at night.

F
Anonymous review+3
36-45 y.o. · 5/21/2026
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